.406 Ventures

Trip Hofer

Venture Partner

Trip joined .406 in 2023 and brings decades of experience running healthcare companies to the firm. In addition to taking on the role of CEO of .406 portfolio company Redox, he helps identify and evaluate new investment opportunities and advises other portfolio companies.

Prior to joining .406, Trip was CEO of Optum Behavioral Solutions, the largest provider of mental health services in the United States. He assumed that role shortly after leading the sale of his previous company, virtual mental health care provider (and .406 portfolio company) AbleTo, to Optum in 2020. Before AbleTo, Trip held leadership roles at CVS Health (where he led acquired companies including Accordant and Novologix), Health Dialog (a .406 portfolio company), and UnitedHealth Group. 

Trip started his career at Booz Allen, a leading management consulting firm headquartered in Washington, D.C., before taking a series of senior roles supporting the Office of the Mayor of Washington, D.C.

Trip received a BA in economics and environmental studies from St. Lawrence University and an MBA from Yale School of Management. 

Meet More of the .406 Team

  • How I want entrepreneurs to perceive me

    Transparent, humble, and well-versed on the healthcare ecosystem

  • Worst fear

    Snakes…I hate snakes.

  • Favorite destination

    Any ski resort out West

  • What you’ll find me drinking

    Seltzers. I drink a lot of seltzer water.

  • Least favorite job

    In high school I worked at Costco preparing and handing out food samples.

  • Best part of the day

    Early morning – right after I get up and the house is still quiet. (I get up before anyone else in my house).

  • Grew up in

    Southborough, MA

  • I can’t stop eating

    Thai food

  • I'm terrible at

    Learning foreign languages

  • Key to successful leadership

    Surrounding yourself with amazing team members

  • Most important lesson learned

    Always put yourself in others’ “shoes” when trying to solve problems and create successful strategies.

  • Key to success

    Listening, in particular, active listening

  • Peak of my athletic career

    Beer league hockey post college

  • Why I chose VC

    I love the innovation and spirit that comes from early-stage companies.

  • First thing you do when you get up

    I go online and check local, national, and international news, and sports highlights.

  • Most rewarding advice

    Change your mindset and approach from “no, because” to “yes, if.”

  • What makes you unique

    My grey hairs, which started to appear at the age of 21

  • Item you have to have on an airplane

    Chargers (of all kinds) to ensure I do not lose power