News & Insights
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Stay up to date with the .406 ecosystem of companies and thinkers.
Latest News
July 20, 2026
Trilio and OSIE Announce Strategic Partnership to Deliver Integrated Data Protection and Billing for OpenStack MSP Environments
Joint solution equips managed service providers with enterprise-grade backup, recovery, and Backup as a Service billing capabilities — as VMware migrations accelerate OpenStack adoption worldwide
- Cybersecurity
- Data + AI
July 7, 2026
Indico Data Recognized in Three Gartner Hype Cycle Reports as the Front Door of Insurance Becomes a Strategic Priority
Company cited in 2026 Hype Cycle reports for Property and Casualty Insurance, Artificial Intelligence in Insurance, and Life Insurance
- Data + AI
July 7, 2026
InStride Peer-Reviewed Research Shows Reduced Caregiver Strain
InStride Health’s New Peer-Reviewed Research Demonstrates Reductions in Caregiver Strain following Specialty Virtual Care for Families of Youth with Anxiety and OCD
- Healthcare
June 25, 2026
Humata Health Expands Reach of Prior Authorization Technology to Independent Practices, Regional Health Centers and Specialty Clinics
New portal extends Humata's AI-powered prior authorization and medical necessity technology to markets where nearly half of all prior authorization requests are still submitted by phone, fax or mail
- Healthcare
June 23, 2026
Redox Launches AI Capabilities Built to Scale Integration Teams and Serve as the Data Foundation for AI in Healthcare
New MCP server, AI Assistant Suite, and intelligent in-flight data processing features help organizations scale: smarter integration workflows for their teams, and a trusted data infrastructure layer for their AI investments
- Healthcare
- Data + AI
June 22, 2026
Life After Cancer: Moving Beyond Your ‘New Normal’
Cancer Treatment Can Leave Lasting Effects — And Many Are Treatable
- Healthcare
June 18, 2026
FamilyWell Health Launches Menopause Hub, Setting the Standard for Behavioral Health in Midlife Care
Program introduces free clinical guidelines for women’s health providers and a comprehensive behavioral health certification for coaches and clinicians
- Healthcare
June 16, 2026
AI Frontier Models’ Potential Threats to SAP Systems Explored in Latest Onapsis Docuseries Episode Debuting June 25
Onapsis security team demonstrates how to protect against real-world scenarios of hackers leveraging AI models to take advantage of vulnerabilities in SAP systems
- Cybersecurity
June 15, 2026
InStride Announces $30M in Series C Funding
InStride, the most trusted, insurance-covered specialty program for young people living with complex anxiety, OCD, and related disorders, raised a $30M Series C from new strategic investors Echo Health Ventures and FMZ Ventures, with continued participation from existing backers: .406 Ventures, Valtruis, General Catalyst, and Mass General Brigham Ventures.
- Healthcare
Investment Stories
June 16, 2026
Prior Authorization Is Having a Moment. Our Two Bets to Address a Broken Process.
Prior authorization has long been one of the most broken parts of the US healthcare system. Providers spend hundreds of hours a week on it.
- Healthcare
April 22, 2025
In the Zone | Our Investment in NaceAI
"AI should work for enterprises, not the other way around. Our MetaModel shapes AI around your business—task-specific and policy-aligned." — Dos Baha, Founder and CEO of NaceAI
- Data + AI
March 11, 2025
In the Zone | Our Investment in Bluebird Kids Health
“Bluebird Kids Health is a committed, multi-disciplinary team of people that’s changing pediatric care, one child at a time.” – Chris Johnson, CEO of Bluebird Kids
- Healthcare
January 30, 2025
In the Zone | Our Investment in Mindgard
“All software has security risks, and AI is no exception. The challenge is that the way these risks manifest within AI is fundamentally different from other software. Drawing on our 10 years of experience in AI security research, Mindgard was created to tackle this challenge. We’re proud to lead the charge toward creating a safer, more secure future for AI.”– Peter Garraghan, Co-founder and CEO of Mindgard
- Cybersecurity
- Data + AI
May 29, 2024
In the Zone | Our Investment in OncoveryCare
“At OncoveryCare, we believe cancer survivorship is the next frontier in cancer care. And in order to build a radical new approach to this phase of care, we knew we had to bring together a dream team of collaborators and investors who were knowledgeable and passionate about this space—and the team at .406 was the perfect partner.”– Hil Moss, Founder & CEO of OncoveryCare
- Healthcare
February 29, 2024
In the Zone | Our Investment in FamilyWell
“I had difficulty finding support when I experienced postpartum depression and have cared for countless new moms struggling to access mental health care during one of the most vulnerable periods of their lives. My experience, both as a survivor and as a practicing neonatologist, inspired me to start FamilyWell to provide equitable, affordable, and accessible mental healthcare for new mothers.” – Dr. Jessica Gaulton, MD MPH, Founder of FamilyWell
- Healthcare
July 20, 2023
In the Zone | Our Investment Portrait Analytics
“I’ve spent most of my career as a hedge fund analyst, and we are building the tool I always wished I had when I was researching businesses.”– David Plon, Co-Founder and CEO of Portrait Analytics
- Data + AI
April 25, 2023
In the Zone | Our Investment in Bobsled
“Bobsled’s data sharing platform enables data providers, SaaS companies, and data teams to share analytics-ready data products natively into a consumer’s data lake or warehouse, enabling their customers to spend less time on data wrangling and more time generating insights.”– Jake Graham, Co-Founder and CEO of Bobsled
- Data + AI
Podcasts
May 19, 2026
Breaking Health Podcast
Payal Agrawal Divakaran with Sofia Noori: How PTSD Recovery is Possible
- Healthcare
January 20, 2026
Breaking Health Podcast
Payal Agrawal Divakaran with Jess Gaulton: Women’s Mental Healthcare at All Stages
- Healthcare
January 6, 2026
Technoventure
Liam Donohue on Fixing U.S. Healthcare: Why AI Alone Won’t Save It
- Healthcare
November 20, 2025
Expanding Access Podcast
Liam Donohue – Mental Health’s Role in Accelerating Recovery From Workplace Injury
- Healthcare
August 19, 2025
Breaking Health Podcast
Payal Agrawal Divakaran: Medicaid Innovation and Sustainable Ventures
- Healthcare
July 17, 2025
Bloomberg Intelligence: Vanguards of Health Care
Payal Agrawal Divakaran on .406 Ventures’ Early-Stage Strategy
- Healthcare
May 13, 2025
Breaking Health Podcast
Payal Agrawal Divakaran with Jeremy Friese: Solving Prior Authorization from Both Sides
- Healthcare
February 18, 2025
Breaking Health Podcast
Payal Agrawal Divakaran with Jeffrey Wessler: Providing Virtual Cardiovascular Healthcare
- Healthcare
January 22, 2025
The VentureFizz Podcast
Graham Brooks – Partner, .406 Ventures (Episode 366)
- Data + AI
December 17, 2024
Breaking Health Podcast
Payal Agrawal Divakaran with Kate Condliffe: Accessible Maternity Care and the Future of Women’s Health
- Healthcare
October 22, 2024
Breaking Health Podcast
Payal Agrawal Divakaran with Kristina Saffran: Accessible Eating Disorder Treatments, Choosing Cofounders, More
- Healthcare
September 20, 2023
Venture Daily
Greg Dracon: Klaviyo NYSE Debut, DeepMind Predicts Gene Mutations, AI Security
- Data + AI
August 22, 2023
Venture Daily
Liam Donohue: Arm Files IPO, Corporate VCs Selling Assets, Boston is the New VC Hub
December 8, 2021
PointHealthTech Podcast
Payal Agrawal Divakaran: Why Payers Actually Have the Most Aligned Incentives to Change Healthcare
- Healthcare
March 15, 2021
The VentureFizz Podcast
Payal Agrawal Divakaran and Kathryn Taylor Reddy – .406 Ventures (Episode 210)
- Healthcare