
Joe SantaBarbara
Chief Financial Officer

Joe SantaBarbara joined .406 in 2019 and serves as the firm’s Chief Financial Officer. He brings over a decade of experience in private equity and venture capital, with deep expertise in finance, M&A, and fund operations.
Before .406, Joe was a Senior Manager at Summit Partners, a growth equity firm focused on healthcare, technology, and consumer sectors. There, he led key financial initiatives, including fund management, portfolio company reporting, and equity valuation.
Earlier in his career, Joe was a Senior Associate at PwC, where he specialized in the Life Sciences and Pharmaceutical sector.
Joe holds an MBA from the Kenan-Flagler Business School at the University of North Carolina at Chapel Hill and a BS in Accounting from Stonehill College. He is also a Certified Public Accountant (CPA).

How I want entrepreneurs to perceive the .406 team
As an extension of their core team, working in collaboration to achieve success.
Favorite destination
Maui, Hawaii.
Worst fear
Not living up to potential!
Grew up in
A small town on the North Shore of MA.
I can’t live without
My wife and two beautiful daughters!
I’m terrible at
Standing still; I am constantly searching for a new challenge.
Why I chose VC
I have the opportunity to work with the smartest entrepreneurs and investors in the world on a daily basis; there isn’t a better industry in which to grow as a professional.
Your nickname
Joey / Joe, either one works for me