News & Insights
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Stay up to date with the .406 ecosystem of companies and thinkers.
Latest News
September 15, 2025
Simon AI Launches Agentic Marketing Platform to Unlock Data for Contextual Personalization
Simon AI acts as a marketer’s data and execution team, uncovering hidden signals, activating real-world context, and accelerating high-performing launches that elevate customer experiences
- Data + AI
September 10, 2025
Onapsis Announces New Integration with CrowdStrike Falcon® Next-Gen SIEM
Onapsis today announced a new integration with CrowdStrike Falcon® Next-Gen SIEM, now available on the CrowdStrike Marketplace. The integration enables customers to ingest Onapsis Research Labs’ SAP-focused threat intelligence into Falcon Next-Gen SIEM, helping security teams accelerate investigation, triage, and response for SAP-related threats.
- Cybersecurity
September 9, 2025
On Belay Health Solutions Achieves Medicare Shared Savings, Demonstrating Commitment to High-Quality, Cost-Effective Care.
On Belay Health Solutions, a physician owned and operated Accountable Care Organization (ACO) dedicated to improving the quality of care while reducing costs, is proud to announce that it has successfully achieved Medicare Shared Savings for the 2024 Performance Period, their second year in MSSP.
- Healthcare
September 9, 2025
Ascend Learning Acquires Laudio to Accelerate Innovation in Frontline Healthcare Leadership
Acquisition further expands Ascend’s tech-enabled workforce management offerings
- Healthcare
September 8, 2025
Tech Mahindra and Abacus Insights Partner to Accelerate CMS Interoperability Compliance for U.S. Healthcare Payers
Tech Mahindra (NSE: TECHM), a leading global provider of technology consulting and digital solutions to enterprises across industries and Abacus Insights, the industry leader in data usability and interoperability for U.S. healthcare payers, announced a strategic partnership to enable seamless compliance and modernize healthcare data interoperability.
- Healthcare
- Data + AI
September 2, 2025
Indico Data Achieves Record ARR, 60% New Logo Growth as Global Carriers Leverage Industry’s First Agentic Decisioning Platform
Surging demand for decision automation in commercial and specialty insurance fuels Indico’s record ARR gains and global expansion
- Data + AI
August 20, 2025
America’s Top Venture Capital Firms of 2025
Over the past 50 years, venture capital firms have shaped the U.S. economy into the capitalist behemoth it is today. Many of the biggest companies in the world by market cap, including Apple, NVIDIA, Microsoft, Amazon, and Meta, owe their success in part to VC firms that funded them as they were just starting out, making the VC firms themselves some of the most influential businesses on the planet.
time.com
August 19, 2025
Simon Data evolves marketing with Composable AI Agents built on Snowflake Cortex AI
Marketers have long struggled to turn data into fast, contextual personalization. Simon Data solves that challenge, helping teams understand their customers and deliver personalized experiences across every channel.
- Data + AI
August 18, 2025
RAD Security Joins NVIDIA Inception
RAD Security is pleased to announce that we have joined NVIDIA Inception, a program that nurtures startups revolutionizing industries with technological advancements.
- Cybersecurity
Investment Stories

April 22, 2025
In the Zone | Our Investment in NaceAI
"AI should work for enterprises, not the other way around. Our MetaModel shapes AI around your business—task-specific and policy-aligned." — Dos Baha, Founder and CEO of NaceAI
- Data + AI

March 11, 2025
In the Zone | Our Investment in Bluebird Kids Health
“Bluebird Kids Health is a committed, multi-disciplinary team of people that’s changing pediatric care, one child at a time.” – Chris Johnson, CEO of Bluebird Kids
- Healthcare

January 30, 2025
In the Zone | Our Investment in Mindgard
“All software has security risks, and AI is no exception. The challenge is that the way these risks manifest within AI is fundamentally different from other software. Drawing on our 10 years of experience in AI security research, Mindgard was created to tackle this challenge. We’re proud to lead the charge toward creating a safer, more secure future for AI.”– Peter Garraghan, Co-founder and CEO of Mindgard
- Cybersecurity
- Data + AI

May 29, 2024
In the Zone | Our Investment in OncoveryCare
“At OncoveryCare, we believe cancer survivorship is the next frontier in cancer care. And in order to build a radical new approach to this phase of care, we knew we had to bring together a dream team of collaborators and investors who were knowledgeable and passionate about this space—and the team at .406 was the perfect partner.”– Hil Moss, Founder & CEO of OncoveryCare
- Healthcare

February 29, 2024
In the Zone | Our Investment in FamilyWell
“I had difficulty finding support when I experienced postpartum depression and have cared for countless new moms struggling to access mental health care during one of the most vulnerable periods of their lives. My experience, both as a survivor and as a practicing neonatologist, inspired me to start FamilyWell to provide equitable, affordable, and accessible mental healthcare for new mothers.” – Dr. Jessica Gaulton, MD MPH, Founder of FamilyWell
- Healthcare

July 20, 2023
In the Zone | Our Investment Portrait Analytics
“I’ve spent most of my career as a hedge fund analyst, and we are building the tool I always wished I had when I was researching businesses.”– David Plon, Co-Founder and CEO of Portrait Analytics
- Data + AI

April 25, 2023
In the Zone | Our Investment in Bobsled
“Bobsled’s data sharing platform enables data providers, SaaS companies, and data teams to share analytics-ready data products natively into a consumer’s data lake or warehouse, enabling their customers to spend less time on data wrangling and more time generating insights.”– Jake Graham, Co-Founder and CEO of Bobsled
- Data + AI
Podcasts

August 19, 2025
Breaking Health Podcast
Payal Agrawal Divakaran: Medicaid Innovation and Sustainable Ventures
- Healthcare

July 17, 2025
Bloomberg Intelligence: Vanguards of Health Care
Payal Agrawal Divakaran on .406 Ventures’ Early-Stage Strategy
- Healthcare

May 13, 2025
Breaking Health Podcast
Payal Agrawal Divakaran with Jeremy Friese: Solving Prior Authorization from Both Sides
- Healthcare

February 18, 2025
Breaking Health Podcast
Payal Agrawal Divakaran with Jeffrey Wessler: Providing Virtual Cardiovascular Healthcare
- Healthcare

January 22, 2025
The VentureFizz Podcast
Graham Brooks – Partner, .406 Ventures (Episode 366)
- Data + AI

December 17, 2024
Breaking Health Podcast
Payal Agrawal Divakaran with Kate Condliffe: Accessible Maternity Care and the Future of Women’s Health
- Healthcare

October 22, 2024
Breaking Health Podcast
Payal Agrawal Divakaran with Kristina Saffran: Accessible Eating Disorder Treatments, Choosing Cofounders, More
- Healthcare

September 20, 2023
Venture Daily
Greg Dracon: Klaviyo NYSE Debut, DeepMind Predicts Gene Mutations, AI Security
- Data + AI

August 22, 2023
Venture Daily
Liam Donohue: Arm Files IPO, Corporate VCs Selling Assets, Boston is the New VC Hub

December 8, 2021
PointHealthTech Podcast
Payal Agrawal Divakaran: Why Payers Actually Have the Most Aligned Incentives to Change Healthcare
- Healthcare

March 15, 2021
The VentureFizz Podcast
Payal Agrawal Divakaran and Kathryn Taylor Reddy – .406 Ventures (Episode 210)
- Healthcare