News & Insights
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Stay up to date with the .406 ecosystem of companies and thinkers.
Latest News
October 20, 2025
Reltio announces general availability of Reltio AgentFlow, powering the agentic enterprise.
Industry-leading agentic AI operations suite built for real-time data intelligence from secure, trusted data is now available on all major cloud providers.
- Data + AI
October 17, 2025
Gabrielle Union Joins Nema Health as Investor & Strategic Advisor
Today, we’re deeply honored to share a new step toward achieving our mission: actress, producer, and best-selling author Gabrielle Union has joined Nema as both an investor and advisor.
- Healthcare
October 16, 2025
Redox and Kno2 Form Strategic Alliance to Transform Healthcare Data Exchange Nationwide
Redox, healthcare’s leading interoperability company powering flexible data exchange in real-time, and Kno2, the company leading the future of healthcare communication and a federally designated Qualified Health Information Network (QHIN), today announced a strategic alliance that solves healthcare’s dual challenge of moving clinical data at scale between the major healthcare networks and systems as well as making it instantly usable.
- Healthcare
- Data + AI
October 7, 2025
Mindgard Ups the Ante for Security of AI – Appoints Proven Cybersecurity Leader James Brear to Capture Expanding Market Opportunity
Mindgard, the leading provider of Artificial Intelligence security solutions, today announced the appointment of James Brear as Chief Executive Officer.
- Cybersecurity
- Data + AI
October 7, 2025
Reltio Appoints Industry Veterans Alyson Welch as Chief Revenue Officer and Trish Hayward as ChiefAI Business Transformation Officer
Seasoned executives join Reltio’s leadership team to support its accelerated growth in the agentic AI era.
- Data + AI
October 7, 2025
Telmai Brings Autonomous-Ready Data Observability for the Agentic AI Era
Telmai's new Data Reliability Agents deliver AI-ready data at the lake, validated in real-time, with autonomous detection, resolution, and natural language interfaces for agentic workflows.
- Data + AI
October 3, 2025
Telmai + Atlan unify trust and context to scale autonomous enterprise AI systems
AI pilots fail not because models don’t work, but because data systems lack reliability and context. To scale AI responsibly, enterprises need validated data at the source and metadata enriched with health and governance signals. This article shows how Telmai and Atlan close this gap. Telmai validates data as it lands, while Atlan’s Metadata Lakehouse adds lineage and governance to create the trusted foundation for scaling AI.
- Data + AI
October 2, 2025
The Top 25 Healthcare Software Executives of 2025
The Healthcare Technology Report is pleased to announce The Top 25 Healthcare Software Executives of 2025.
- Healthcare
- Data + AI
thehealthcaretechnologyreport.com
October 1, 2025
Gabrielle Union Joins The Women-Founded Startup That’s Healing Her PTSD
Union has lived with post-traumatic stress disorder (PTSD) for over thirty years since being sexually assaulted at gunpoint at age 19. Despite decades of therapy, trauma dictated much of her life and true peace remained out of reach—until recently. Through the evidence-based treatment she’s received from Nema Health, an online platform for trauma treatment, recovery has finally begun to feel possible.
- Healthcare
forbes.com
Investment Stories
April 22, 2025
In the Zone | Our Investment in NaceAI
"AI should work for enterprises, not the other way around. Our MetaModel shapes AI around your business—task-specific and policy-aligned." — Dos Baha, Founder and CEO of NaceAI
- Data + AI
March 11, 2025
In the Zone | Our Investment in Bluebird Kids Health
“Bluebird Kids Health is a committed, multi-disciplinary team of people that’s changing pediatric care, one child at a time.” – Chris Johnson, CEO of Bluebird Kids
- Healthcare
January 30, 2025
In the Zone | Our Investment in Mindgard
“All software has security risks, and AI is no exception. The challenge is that the way these risks manifest within AI is fundamentally different from other software. Drawing on our 10 years of experience in AI security research, Mindgard was created to tackle this challenge. We’re proud to lead the charge toward creating a safer, more secure future for AI.”– Peter Garraghan, Co-founder and CEO of Mindgard
- Cybersecurity
- Data + AI
May 29, 2024
In the Zone | Our Investment in OncoveryCare
“At OncoveryCare, we believe cancer survivorship is the next frontier in cancer care. And in order to build a radical new approach to this phase of care, we knew we had to bring together a dream team of collaborators and investors who were knowledgeable and passionate about this space—and the team at .406 was the perfect partner.”– Hil Moss, Founder & CEO of OncoveryCare
- Healthcare
February 29, 2024
In the Zone | Our Investment in FamilyWell
“I had difficulty finding support when I experienced postpartum depression and have cared for countless new moms struggling to access mental health care during one of the most vulnerable periods of their lives. My experience, both as a survivor and as a practicing neonatologist, inspired me to start FamilyWell to provide equitable, affordable, and accessible mental healthcare for new mothers.” – Dr. Jessica Gaulton, MD MPH, Founder of FamilyWell
- Healthcare
July 20, 2023
In the Zone | Our Investment Portrait Analytics
“I’ve spent most of my career as a hedge fund analyst, and we are building the tool I always wished I had when I was researching businesses.”– David Plon, Co-Founder and CEO of Portrait Analytics
- Data + AI
April 25, 2023
In the Zone | Our Investment in Bobsled
“Bobsled’s data sharing platform enables data providers, SaaS companies, and data teams to share analytics-ready data products natively into a consumer’s data lake or warehouse, enabling their customers to spend less time on data wrangling and more time generating insights.”– Jake Graham, Co-Founder and CEO of Bobsled
- Data + AI
Podcasts
August 19, 2025
Breaking Health Podcast
Payal Agrawal Divakaran: Medicaid Innovation and Sustainable Ventures
- Healthcare
July 17, 2025
Bloomberg Intelligence: Vanguards of Health Care
Payal Agrawal Divakaran on .406 Ventures’ Early-Stage Strategy
- Healthcare
May 13, 2025
Breaking Health Podcast
Payal Agrawal Divakaran with Jeremy Friese: Solving Prior Authorization from Both Sides
- Healthcare
February 18, 2025
Breaking Health Podcast
Payal Agrawal Divakaran with Jeffrey Wessler: Providing Virtual Cardiovascular Healthcare
- Healthcare
January 22, 2025
The VentureFizz Podcast
Graham Brooks – Partner, .406 Ventures (Episode 366)
- Data + AI
December 17, 2024
Breaking Health Podcast
Payal Agrawal Divakaran with Kate Condliffe: Accessible Maternity Care and the Future of Women’s Health
- Healthcare
October 22, 2024
Breaking Health Podcast
Payal Agrawal Divakaran with Kristina Saffran: Accessible Eating Disorder Treatments, Choosing Cofounders, More
- Healthcare
September 20, 2023
Venture Daily
Greg Dracon: Klaviyo NYSE Debut, DeepMind Predicts Gene Mutations, AI Security
- Data + AI
August 22, 2023
Venture Daily
Liam Donohue: Arm Files IPO, Corporate VCs Selling Assets, Boston is the New VC Hub
December 8, 2021
PointHealthTech Podcast
Payal Agrawal Divakaran: Why Payers Actually Have the Most Aligned Incentives to Change Healthcare
- Healthcare
March 15, 2021
The VentureFizz Podcast
Payal Agrawal Divakaran and Kathryn Taylor Reddy – .406 Ventures (Episode 210)
- Healthcare