News & Insights
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Stay up to date with the .406 ecosystem of companies and thinkers.
Latest News
August 20, 2025
America’s Top Venture Capital Firms of 2025
Over the past 50 years, venture capital firms have shaped the U.S. economy into the capitalist behemoth it is today. Many of the biggest companies in the world by market cap, including Apple, NVIDIA, Microsoft, Amazon, and Meta, owe their success in part to VC firms that funded them as they were just starting out, making the VC firms themselves some of the most influential businesses on the planet.
time.com
August 12, 2025
Heartbeat Health Earns 227th Rank on the 2025 Inc. 5000 List of America’s Fastest-Growing Private Companies
With three years of rapid revenue growth, this marks Heartbeat Health's first time on the list
- Healthcare
August 5, 2025
Reltio Unveils AgentFlow, A Set of Agents for Data Governance and Business Operations
Reltio AgentFlow, built on Reltio Data Cloud, delivers autonomous agents purpose-built for critical jobs using unified, trusted enterprise data.
- Data + AI
August 4, 2025
Laudio Adds Two New Health System Executives to its Strategic Advisory Council
Laudio, an innovator in frontline leader solutions that drive efficiency and engagement for health systems, today announced the addition of two new members – Brion Lieberman and Lorie Rhine – to its Strategic Advisory Council (SAC).
- Healthcare
July 30, 2025
Wayspring and Delaware First Health Join Forces to Advance Substance Use Disorder Treatment
Delaware residents impacted by substance use disorder (SUD) now have greater access to life-changing care through a new partnership between Delaware First Health, a Medicaid Managed Care Organization, and Wayspring.
- Healthcare
July 29, 2025
Portrait Analytics and Third Bridge Partner to Deliver Ai-Driven Investment Research with Human Insight
The new partnership combines Third Bridge's world leading library of expert interviews with Portrait's AI-driven research tools, streamlining how institutional investors blend qualitative insight with quantitative analysis.
- Data + AI
July 22, 2025
InStride Health Strengthens Executive Team with Appointment of Chief Commercial Officer and Chief Financial Officer
Veteran consumer and healthcare leaders will support InStride’s mission to scale evidence-based pediatric mental health care
- Healthcare
July 21, 2025
OncoveryCare Welcomes Dr. Catherine Alfano as Chief Product & Strategy Officer to Build the Future of Survivorship Care
OncoveryCare, which delivers virtual, whole-person care to cancer survivors, today announced that Catherine M. Alfano, PhD, has joined as Chief Product & Strategy Officer.
- Healthcare
July 16, 2025
Nomad Health Recognized Among SIA’s 2025 Fastest-Growing Staffing Firms in the U.S.
Nomad Health, the leading travel clinician marketplace, announces it has been ranked #42 on Staffing Industry Analysts’ (SIA) 2025 list of the Fastest-Growing Staffing Firms in the United States, a prestigious ranking that recognizes exceptional revenue growth and industry impact across the staffing sector.
- Healthcare
Investment Stories

April 22, 2025
In the Zone | Our Investment in NaceAI
"AI should work for enterprises, not the other way around. Our MetaModel shapes AI around your business—task-specific and policy-aligned." — Dos Baha, Founder and CEO of NaceAI
- Data + AI

March 11, 2025
In the Zone | Our Investment in Bluebird Kids Health
“Bluebird Kids Health is a committed, multi-disciplinary team of people that’s changing pediatric care, one child at a time.” – Chris Johnson, CEO of Bluebird Kids
- Healthcare

January 30, 2025
In the Zone | Our Investment in Mindgard
“All software has security risks, and AI is no exception. The challenge is that the way these risks manifest within AI is fundamentally different from other software. Drawing on our 10 years of experience in AI security research, Mindgard was created to tackle this challenge. We’re proud to lead the charge toward creating a safer, more secure future for AI.”– Peter Garraghan, Co-founder and CEO of Mindgard
- Cybersecurity
- Data + AI

May 29, 2024
In the Zone | Our Investment in OncoveryCare
“At OncoveryCare, we believe cancer survivorship is the next frontier in cancer care. And in order to build a radical new approach to this phase of care, we knew we had to bring together a dream team of collaborators and investors who were knowledgeable and passionate about this space—and the team at .406 was the perfect partner.”– Hil Moss, Founder & CEO of OncoveryCare
- Healthcare

February 29, 2024
In the Zone | Our Investment in FamilyWell
“I had difficulty finding support when I experienced postpartum depression and have cared for countless new moms struggling to access mental health care during one of the most vulnerable periods of their lives. My experience, both as a survivor and as a practicing neonatologist, inspired me to start FamilyWell to provide equitable, affordable, and accessible mental healthcare for new mothers.” – Dr. Jessica Gaulton, MD MPH, Founder of FamilyWell
- Healthcare

July 20, 2023
In the Zone | Our Investment Portrait Analytics
“I’ve spent most of my career as a hedge fund analyst, and we are building the tool I always wished I had when I was researching businesses.”– David Plon, Co-Founder and CEO of Portrait Analytics
- Data + AI

April 25, 2023
In the Zone | Our Investment in Bobsled
“Bobsled’s data sharing platform enables data providers, SaaS companies, and data teams to share analytics-ready data products natively into a consumer’s data lake or warehouse, enabling their customers to spend less time on data wrangling and more time generating insights.”– Jake Graham, Co-Founder and CEO of Bobsled
- Data + AI
Podcasts

July 17, 2025
Bloomberg Intelligence: Vanguards of Health Care
Payal Agrawal Divakaran on .406 Ventures’ Early-Stage Strategy
- Healthcare

May 13, 2025
Breaking Health Podcast
Payal Agrawal Divakaran with Jeremy Friese: Solving Prior Authorization from Both Sides
- Healthcare

February 18, 2025
Breaking Health Podcast
Payal Agrawal Divakaran with Jeffrey Wessler: Providing Virtual Cardiovascular Healthcare
- Healthcare

January 22, 2025
The VentureFizz Podcast
Graham Brooks – Partner, .406 Ventures (Episode 366)
- Data + AI

December 17, 2024
Breaking Health Podcast
Payal Agrawal Divakaran with Kate Condliffe: Accessible Maternity Care and the Future of Women’s Health
- Healthcare

October 22, 2024
Breaking Health Podcast
Payal Agrawal Divakaran with Kristina Saffran: Accessible Eating Disorder Treatments, Choosing Cofounders, More
- Healthcare

September 20, 2023
Venture Daily
Greg Dracon: Klaviyo NYSE Debut, DeepMind Predicts Gene Mutations, AI Security
- Data + AI

August 22, 2023
Venture Daily
Liam Donohue: Arm Files IPO, Corporate VCs Selling Assets, Boston is the New VC Hub

December 8, 2021
PointHealthTech Podcast
Payal Agrawal Divakaran: Why Payers Actually Have the Most Aligned Incentives to Change Healthcare
- Healthcare

March 15, 2021
The VentureFizz Podcast
Payal Agrawal Divakaran and Kathryn Taylor Reddy – .406 Ventures (Episode 210)
- Healthcare