
About
We believe great companies start with great relationships.
We’re in it with you from the very beginning.
Who We Are
We’re on
your team.
Every investment we make is a meaningful partnership. That means we deliver both capital and practical resources—including sharing scar tissue, late-night brainstorming sessions, and early-morning navigation of challenges—to give you the power and know-how to build your company.
We use a lot of different metrics to measure our performance as investors. But the one we’re most proud of is that 17 founders (so far) have come back to team up with us a second time to build their next companies.




.406 has been an incredible partner across both of my companies. When I needed help, they stepped up—not just with capital but with real support, insight, and a willingness to get in the trenches. When it came time to found Mythica, they were the obvious choice; they understood our vision and moved fast to back us again.”

“I started working with .406 Ventures in 2015 when I became CEO of one of their portfolio companies. I had such a great experience that I became an Executive in Residence and we incubated, built, and sold a company together. Since then, I’ve been an advisor to several companies in the .406 portfolio. From concept to exit, .406 Ventures is always side by side with me as we build together.”
– Tom Torre, CEO, Xformative and Co-founder and former CEO and Board Member, Bend Financial
$23B+
of value and growing
94
portfolio
companies
~8,000
people employed across our current portfolio
20%+
repeat entrepreneurs with .406
130+
graduated student fellows
1st
investor in several category-defining companies
$1.3B+
capital under management
Our Philosophy
Our name and logo design get to the heart of who we are—and both pay tribute to Boston and Red Sox legend Ted Williams.
For those unfamiliar (or, heaven forbid, Yankee fans), Boston Red Sox legend Ted Williams achieved an unsurpassed .406 batting average in the 1941 baseball season. Ted was rare in that he understood that while a pitch may be a strike, swinging at only those uniquely suited to his swing, in what he called his “happy zone,” would maximize his chance of success. So he let a lot of strikes go as he became the best hitter to have ever lived.
We embrace the same philosophy in our investment strategy. There are a lot of great opportunities out there, but playing to our strengths and knowing where we have the best chance to hit it out of the park is at the core of how we work.




Our Team
Decades of experience delivered by
real people.
In late 2005, Larry Begley, Maria Cirino, and Liam Donohue set out to build a venture firm composed of the kind of investors they would have wanted themselves: people committed to getting in the trenches and staying there with you for the long haul.
We want to earn the right to be the board member you call first – whether you need to share good or bad news. We understand how hard it is to build pioneering companies and seek to bring our perspective, scar tissue, and advice as a hands-on partner without any pontification or arrogance.
Our Programs


