.406 Ventures

Maria Cirino

Co-Founder and Managing Partner

Maria has been building and founding technology businesses for 25 years. Her operational, entrepreneurial and senior management experience in venture-backed technology companies includes two Massachusetts IPOs of the Year and the founding of two successful companies and a venture capital firm.

Prior to co-founding .406 Ventures in 2006, Maria served as an SVP of VeriSign following its 2005 acquisition of Guardent, the market leading Managed Security Services provider for $142 million. Guardent was a Sequoia, Charles River Ventures and NEA-backed IT security company that Maria co-founded and led as CEO. In this role, Maria received industry recognition as "Massachusetts CEO of the Year" and "Ernst & Young Entrepreneur of the Year," among others.

Prior to Guardent, Maria was Senior Vice President responsible for sales and marketing at Razorfish, an IT services company that acquired her previous company, i-Cube, for $1.8 billion in 1999. At i-Cube, Maria led sales and marketing. Prior to i-Cube, from 1993 – 1997, Maria was responsible for North American sales at Shiva, the category-creating remote access leader. Prior to Shiva, Maria held sales and marketing roles at Lotus Development Corporation and Software City Inc.

Maria holds an AB in English literature from Mount Holyoke College where she has served as a Trustee and as a member of the college's investment committee.

At .406 Ventures, in addition to her investment activities, Maria manages brand building and deal flow strategy. She currently serves on the boards of .406 portfolio companies AuthAir, Carbon Black, Jisto, Kaltura, Lexumo, MineralTree, Onapsis, Pwnie Express, Threat Stack, Vaultive and Veracode. Maria formerly served on the boards of Adtuitive, Digitalsmiths and Memento until their respective acquisitions by Etsy, TiVO and FIS.


Meet More of the .406 Team

  • How I want entrepreneurs to perceive me

    One of them. (With a decade + of relevant investment experience that can be helpful to them).

  • How I want entrepreneurs to perceive the .406 team

    As an extension of their team.

  • Biggest failure

    I don’t believe in failure. I believe in lessons learned and perseverance

  • Favorite book

    A Room With A View by E.M. Forrester

  • Favorite destination

    Any non touristy village in Europe that dates back to the middle ages

  • Something I say all the time

    Get the first 15 hires right and the rest will be easy…

  • Fond childhood memory

    The day my dad took the training wheels off my bike and ran alongside me for about a mile!

  • Grew up in

    A 500 family town in NJ, no traffic signal in town

  • I can’t live without

    My GPS

  • I'm terrible at


  • Key to successful leadership

    Listen more than you talk and when you do talk choose your words carefully

  • Most important lesson learned

    Wash your hands often

  • Key to success

    Never give up and always have big dreams

  • In a past life I

    was a lifeguard

  • Why I chose VC

    VC chose me

  • You are most proud of

    My longstanding relationships with hundreds of former colleagues

  • What makes you unique

    Compact size with big wingspan

  • A nickname for .406 as a whole

    My Peeps

Maria's Portfolio


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